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hypusine biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
[eIF5A-precursor]-N-(4-aminobutylidene)-lysine + NADH + H+ <=> [eIF5A-precursor]-deoxyhypusine + NAD+ 2.5.1.46 deoxyhypusine synthase

[eIF5A-precursor]-N-(4-aminobutylidene)-lysine + [eIF5A-precursor]-lysine <=> [eIF5A-precursor]-N-(4-aminobutylidene)-lysine + [deoxyhypusine_synthase]-L-lysine + H+ not assigned

spermidine + NAD+ <=> dehydrospermidine + NADH + H+ 2.5.1.46 deoxyhypusine synthase

[eIF5A-precursor]-deoxyhypusine + O2 + reduced_acceptor <=> [eIF5A]-hypusine + H2O + acceptor 1.14.99.29 deoxyhypusine monooxygenase

dehydrospermidine + [deoxyhypusine_synthase]-L-lysine <=> [eIF5A-precursor]-N-(4-aminobutylidene)-lysine + 1,3-diaminopropane not assigned

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