|
|
[eIF5A-precursor]-N-(4-aminobutylidene)-lysine + NADH + H+ <=> [eIF5A-precursor]-deoxyhypusine + NAD+
|
2.5.1.46
deoxyhypusine synthase
|
–
|
|
BRENDA:
BR50494
KEGG:
R07478
MetaCyc:
RXN-13417
|
|
|
|
[eIF5A-precursor]-N-(4-aminobutylidene)-lysine + [eIF5A-precursor]-lysine <=> [eIF5A-precursor]-N-(4-aminobutylidene)-lysine + [deoxyhypusine_synthase]-L-lysine + H+
|
not assigned
|
–
|
|
MetaCyc:
RXN-13416
|
|
|
|
spermidine + NAD+ <=> dehydrospermidine + NADH + H+
|
2.5.1.46
deoxyhypusine synthase
|
–
|
|
BRENDA:
BR50491
KEGG:
R07477
MetaCyc:
RXN-13414
|
|
|
|
[eIF5A-precursor]-deoxyhypusine + O2 + reduced_acceptor <=> [eIF5A]-hypusine + H2O + acceptor
|
1.14.99.29
deoxyhypusine monooxygenase
|
–
|
|
MetaCyc:
DEOXYHYPUSINE-MONOOXYGENASE-RXN
|
|
|
|
dehydrospermidine + [deoxyhypusine_synthase]-L-lysine <=> [eIF5A-precursor]-N-(4-aminobutylidene)-lysine + 1,3-diaminopropane
|
not assigned
|
–
|
|
MetaCyc:
RXN-13415
|
|